Publications

Swathi SundarRaj, Abhijeet Deshmukh, Nancy Priya, Vidya S. Krishnan, Murali Cherat, and Anish Sen Majumdar, "Development of a System and Method for Automated Isolation of Stromal Vascular Fraction from Adipose Tissue Lipoaspirate," Stem Cells International, vol. 2015, Article ID 109353, 11 pages, 2015. doi:10.1155/2015/109353

Book Chapter:
R.Pal and Satish Totey. (2009) Application of Human Embryonic SC in drug discovery: A boon to pharmaceutical Industries. Chapter in Book Stem cells: Basic and Applications edited by Kaushik Deb and Satish Totey.

Satish Totey, Swapnil Totey, Rajarshi Pal, Murali Krishna Mamidi, Vijayendran Govindasamy. Stem Cell Biology and Application. Book entitled Application of Flow Cytometry in Stem Cell research and Tissue Regeneration. Aug 2010 WILEY Inc. Publishers; Chapter 2.

Satish Totey, Rakhi Pal, Chuah Chong Boon, K.G. Vijayendran, Rajarshi Pal and Swapnil Totey (2009) MSC: Biology, Culture optimization and potential clinical use. Chapter in Book Stem cells: Basic and Applications edited by Kaushik Deb and Satish Totey.

Anjan K. Das, Pawan K. Gupta, C. H. Anoop, Sudha Balasubramanian,and Anish S. Majumdar: Mesenchymal Stem Cell Therapy for Peripheral Vascular Diseases Chapter in Stem Cell Biology and Regenerative Medicine Stem Cell Biology and Regenerative Medicine, DOI 10.1007/978-1-62703-200-1_18,© Springer Science + Business Media New York 2013 (Book Chapter)

Gottipamula S, Kolkundkar U, Seetharam RN. . "Stem cell Therapeutics – Challenges and Opportunities" in Biotechnology in Health care published by Lap Lambart Academic Publishing, Germany. 2014. (Book Chapter). The role of mesenchymal stem cells in the management of critical limb ischemia (book Review) Pawan K G. (Accepted)

Gottipamula S, Ashwin KM, Muttigi MS, Kannan S, Kolkundkar U, Seetharam RN. Isolation, expansion and characterization of bone marrow derived stem cells in serum free conditions. Journal of Cell and Tissue Research, 2014 Apr;356(1):123-35. doi: 10.1007/s00441-013-1783-7. Epub 2014 Jan 22. PubMed PMID: 24448665

Swamynathan P, Venugopal P, Kannan S, Thej C, Kolkundar UK, Bhagwat S, Ta M, Majumdar AS, Balasubramanian S. Are serum-free and xeno-free culture conditions ideal for large scale clinical grade expansion of Wharton's jelly derived mesenchymal stem cells? A comparative study. Stem Cell Res Ther. 2014 Jul 28;5(4):88. [Epub ahead of print] PubMed PMID: 25069491.

Anoop Chullikana, Anish Sen Majumdar , Sanjay Gottipamula ,Sagar Krishnamurthy, A. Sreenivas Kumar, V.S. Prakash & Pawan Kumar Gupta "Randomized, double-blind, phase I/II study of intravenous allogeneic mesenchymal stromal cells in acute myocardial infarction" Cytotherapy, 2014; 0: 1-12 ( Dec 2014)

Udaykumar Kolkundkar, Sanjay Gottipamula2 and Anish S. Majumdar "Cell Therapy Manufacturing and Quality Control: Current Process and Regulatory Challenges" Review article J Stem Cell Res Ther 2014, 4:9

Noor Atiqah Fakharuzi,Ahmad Zuhairi Abd Rahman,Gurbind Singh, Nurul Ain Nasim Mohd Yusof, Kamal S Fakiruddin, Lim Moon Nian, Puteri J Noor M Baharuddin, Salehhuddin Hamdan, Anish Sen Majumdar, Zubaidah Zakaria "Non-Invasive In Vivo Tracking, Biodistribution And Fate Of Human Mesenchymal Stromal Cells (MSCs) In Rat Model" Regenerative Research 3(2) 2014 128-130

Das AK, Basri A, Dhillon SS, Vijanari A, Anoop CH, Gupta PK: Intra arterial Allogeneic mesenchymal stem cells for critical limb ischemia are safe and efficacious: Report of a Phase I study. J Transl Med. 2013; 11: 143.

Balasubramanian S, Thej C, Venugopal P, Priya N, Zakaria Z, SundarRaj S, Majumdar AS. Higher propensity of Wharton's jelly derived mesenchymal stromal cells towards neuronal lineage in comparison to those derived from adipose and bone marrow.Cell Biol Int. 2013 Jan 31. doi: 10.1002/cbin.10056. [Epub ahead of print]

Dutta S, Singh G, Sreejith S, Mamidi MK, Husin JM, Datta I, Pal R, Das AK. Cell therapy: the final frontier for treatment of neurological diseases. CNS Neurosci Ther. 2013 Jan;19(1):5-11. doi: 10.1111/cns.12027.

Gottipamula S, Muttigi MS, Chaansa S, Ashwin KM, Priya N, Kolkundkar U, SundarRaj S, Majumdar AS, Seetharam RN. Large-scale expansion of pre-isolated bone marrow mesenchymal stromal cells in serum-free conditions. J Tissue Eng Regen Med. 2013 Mar 12. doi: 10.1002/term.1713. [Epub ahead of print] PubMed PMID: 23495227.

Pawan KG et al (2013)., Double Blind Randomized Placebo Controlled Phase I/II study assessing the safety and efficacy of Allogeneic Bone Marrow Derived Mesenchymal Stem Cell in Critical Limb Ischemia. J Transl Med. 2013 Jun 10;11:143. doi: 10.1186/1479-5876-11-143.

Swathi SundarRaj, Nancy Priya, Abhijeet Deshmukh, Murali Cherat and Anish Sen Majumdar(July 2013)., Development of an Automated Device for Point-Of-Care Isolation of Stromal Vascular Fraction Cells from Adipose Tissue Lipoaspirate. IPRAS Journal, July 2013, Issue 13, 43-44.

Pratiksha A Dighe, Pachaiyappan Viswanathan, Ashwin K Mruthunjaya, Raviraja N Seetharam. 2013. Effect of bFGF on HLA-DR expression of human Bone Marrow derived Mesenchymal Stem Cells. Journal of Stem cells, Volume 8 Issue 1.

Gottipamula S, Muttigi MS, Kolkundkar U, Seetharam RN. Serum-free media for the production of human mesenchymal stromal cells: a review. Cell Prolif. 2013 Sep 30. doi: 10.1111/cpr.12063. [Epub ahead of print] PubMed PMID: 24118248.

Rajarshi Pal et.al., (2011), A Simple and economical route to generate functional hepatocyte-like cells from hESCs and their application in evaluating alcohol induced liver damage: J Cell Biochem. 2012 Jan; 113 (1):19-30.

Gottipamula S, Sharma A, Krishnamurthy S, Majumdar AS, Seetharam RN. Human platelet lysate is an alternative to fetal bovine serum for large-scale expansion of bone marrow-derived mesenchymal stromal cells. Biotechnol Lett. 2012 Jul; 34(7):1367-74. doi: 10.1007/s10529-012-0893-8. Epub 2012 Apr 4. PubMed PMID: 22476583.

Bankapur A, Krishnamurthy RS, Zachariah E, Santhosh C, Chougule B, et al. (2012) Micro-Raman Spectroscopy of Silver Nanoparticle Induced Stress on Optically-Trapped Stem Cells. PLoS ONE 7(4): e35075. doi:10.1371/journal.pone.0035075

Pal R, Mamidi MK, Das AK, Bhonde R: Diverse effects of dimethyl sulfoxide (DMSO) on the differentiation potential of human embryonic stem cells Arch Toxicol. 2012 Apr;86(4):651-61.  [PubMed - 22105179] [Impact factor 4.26].

Mamidi MK, Nathan KG, Singh G, Thrichelvam ST, My NA, Fakharuzi NA, Zakaria Z, Bhonde R, Das AK, Majumdar AS. (2012) Comparative cellular and molecular analyses of pooled bone marrow multipotent mesenchymal stromal cells during continues passaging and after successive cryopreservation. J Cell Biochem. 2012 Oct;113(10):3153-64. doi: 10.1002/jcb.24193.

Nancy Priya, Shilpita Sarcar, Anish Sen Majumdar and Swathi SundarRaj,(2012) Explant culture: a simple, reproducible, efficient and economic technique for isolation of mesenchymal stromal cells from human adipose tissue and lipoaspirated Journal of Tissue Engineering and Regenerative Medicine.2012 DOI: 10.1002/term.1569

Murali Krishna Mamidi, Rajarshi Pal, Sovan Dey, Basri Johan Jeet Bin Abdullah, Zubaidah Zakaria, Mahendra S. Rao & Anjan Kumar Das(2012). Cell therapy in critical limb ischemia: current developments and future progress. Cytotherapy Volume 14, Issue 8, September 2012, Pages 902–916

Pawan K. Gupta et al(2012), Mesenchymal Stem Cells for Cartilage Repair in Osteoarthritis Stem cell research and therapy)- 3:25 (9 July 2012)

Anish et al(2012)., A leading Indian Stem cell company Developing cellular therapeutics for global consumers. Telegraft Vol. 19, No. 4 july 2012

Pal R, Mamidi MK, Das AK, and Bhonde R. A comparative analysis of cardiomyocyte differentiation from human embryonic stem cells under 3-D and 2-D culture conditions. J Biosci Bioeng. 2012 Oct 5. doi:pii: S1389-1723(12)00361-1. 10.1016/j.jbiosc.2012.08.018. [Epub ahead of print]

Murali Krishna Mamidi, Gurbind Singh, Juani Mazmin Husin, Kavitha Ganesan Nathan, Gopinath Sasidharan, Zubaidah Zakaria, Ramesh Bhonde, Anish Sen Majumdar, (2012); Impact of passing mesenchymal stem cells through smaller bore size needles for subsequent use in patients for clinical or cosmetic indications J Transl Med. 2012; 10: 229.

Mamidi MK, Pal R, Govindasamy V, Zakaria Z, Bhonde R. (2011) Treat the graft to improve the regenerative ability of the host. Med Hypotheses, April; 776(4):599-601.

Parvathy Venugopal, Sudha Balasubramanian, Anish Sen Majumdar, Malancha Ta. (2011) "Isolation, Characterization and Gene Expression Analysis of Wharton's Jelly-derived Mesenchymal Stem Cells under Xenofree Culture Conditions" Stem Cells and Cloning: Advances and Applications, 4: 39–50.

Govindasamy V, Ronald VS, Abdullah AN, Ganesan Nathan KR, Ab Aziz ZA, Abdullah M, Musa S, Abu Kasim NH, Bhonde RR. (2011) Differentiation of Dental Pulp Stem Cells Into Islet Like Aggregates. J Dent Res. May; 90(5):646-52.

Mamidi MK, Pal R, Binti Mori NA, Arumugam G, Thrichelvam ST, Noor PJ, Farouk Abdullah HM, Gupta PK, Das AK, Zakaria Z and Bhonde R. (2011) Co-culture of mesenchymal-like stromal cells derived from human foreskin permits long term propagation and differentiation of human embryonic stem cells. Journal of Cellular Biochemistry, May; 112(5): 1353-63

Das AK. (2011) Randomised Clinical trials in Surgery: a look at the ethical and practical issues Indian J of Surgery, & 3: 245-250 (DOI 10.1007/s12262-011-0307-5).

Das AK, Gopurappilly R, Parhar IS. (2011) Current status and prospective applications of stem cell-based therapy for spinal cord injury: A challenge for contemporary neurobiology: Curr. Stem Cell Res Ther. 6(2): 93-104.

Gopurappilly R et al(2011)., Stem Cells in Stroke Repair: Current Success & Future Prospects. CNS Neurol Disord Drug Targets. 10: 741-756

Rajarshi Pal, Murali Krishna Mamidi, Anjan Kumar Das and Ramesh Bhonde(2011)., Human embryonic stem cell proliferation and differentiation as parameters to evaluate developmental toxicity. Journal of Cellular Physiology Volume 226, Issue 6, June 2011, Pages: 1583–1595.

VIJAYENDRAN G et al ( 2011) Human platelet lysate permits scale-up of dental pulp stromal cells for clinical applications. Cytotherapy, 1–13

Balasubramanian. S et. al., (2011) Comparison of Chemokine and Receptor Gene Expression between Wharton's Jelly and Bone Marrow Derived Mesenchymal Stem Cells. Cytotherapy 11/2011; 14(1):26-33

Nekanti U, Rao VB, Bahirvani AG, Jan M, Totey S and Ta M. (2010) Long-term Expansion and Pluripotent Marker Array Analysis of Wharton's Jelly-Derived Mesenchymal Stem Cells. Stem Cells Dev, 19(1): 117-130.

Neelam K Venkataramana, V Satishkumar K, Sudheer Balaraju, C.R.Radhika, Abhilash Bansal, Ashish Dixit, Deepthi K.R., Madhulita Das, Majahar Jan, Pawan Kumar Gupta, Satish Totey. (2010) Open labeled study of unilateral autologous bone marrow derived mesenchymal stem cells transplantation in Parkinson's disease. Translational Research, 155(2)62-70.

Prasanna SJ, Gopalakrishnan D, Shankar SR, Vasandan AB. (2010) Pro-Inflammatory Cytokines, IFNγ and TNFα, Influence Immune Properties of Human Bone Marrow and Wharton Jelly Mesenchymal Stem Cells Differentially. PLoS One. 2010 Feb 2;5(2):e9016. doi: 10.1371/journal.pone.0009016.

Sivasubramaniyan K, Pal R, Totey S, Bhat VS, Totey S. (2010) Rho Kinase Inhibitor Y27632 Alters the Balance Between Pluripotency and Early Differentiation Events in Human Embryonic Stem Cells. Curr Stem Cell Res Ther, 5(1):2-12(11).

Mamidi MK, Pal R, Bhonde R, Zakaria Z, Totey S 2010. Application of Multiplex PCR for Characterization of Human Embryonic Stem Cells (hESCs) and Its Differentiated Progenies. J Biomol Screen, 15(6): 630-643.

Das A and Pal R. (2010) Induced pluripotent stem cells (iPSCs): the emergence of a new champion in stem cell technology-driven biomedical applications. J Tissue Eng Regen Med, 4: 413–421. doi: 10.1002/term.258.

Vijayendran Govindasamy, Aimi Naim Abdullah, Veronica Sainik Ronald, Sabri Musa, Zeti Adura Che Ab. Aziz, Rosnah Binti Zain, Satish Totey, Ramesh R. Bhonde, Noor Hayaty Abu Kasim. (2010) Inherent differential propensity of dental pulp stem cells derived from human deciduous and permanent teeth. Journal of endodontics, 36(9); 1504-1515, DOI: 10.1016/j.joen.2010.05.006.

Nekanti U., Dastidar S., Venugopal P., Totey S. and Ta M. (2010) Increased proliferation and analysis of differential gene expression in human Wharton's Jelly-derived mesenchymal stromal cells under hypoxia. Int. J. Biol. Sci,. 6(5):499-512.

Rakhi Pal, Chaitanya Gopinath, Nagesh M Rao, Poulomi Banerjee, Venkatesh Krishnamoorthy, Neelam K. Venkataramana & Satish Totey (Oct 2010). Functional recovery after transplantation of bone marrow-derived human mesenchymal stromal cells in a rat model of spinal cord injury. Cytotherapy, 12(6), 792-806.

Vijayendran Govindasamy, Veronica Sainik Ronald, Swapnil Totey, Salina binti Din, Wan Mahadzir Bin Wan Mustafa, Satish Totey, Zubaidah Zakaria, Ramesh R.Bhonde. (2010) Micromanipulation of culture niche permits long term expansion of dental pulp stem cells - an economic and commercial angle," In Vitro Cell Dev Biol Anim. 46(9):764-73.

Nekanti U., Mohanty L., Venugopal P., Balasubramanian S., Totey S. and Ta M. 2010. Optimization and Scale up of Wharton's Jelly-derived Mesenchymal Stem Cells for Clinical Applications. Stem Cell Res. Nov;5(3):244-54.

Pal R, Hanwate M, Jan M, Totey S. (2009) Phenotypic and functional comparison of optimum culture conditions for upscaling of bone marrow-derived mesenchymal stem cells. J Tissue Eng Regen Med. 2009 Mar;3(3):163-74. doi: 10.1002/term.143.

Pal R. (2009) Embryonic stem (ES) cell-derived cardiomyocytes: a good candidate for cell therapy applications. Cell Biol Int, 33(3): 325-36.

Deb KD. (2009) A sweet potion to put embryonic stem cells to sleep. Scientific World Journal, 9: 236-49.

Das, Anjan Kumar. (2009) Stem cell therapy for critical limb ischemia – a review: Indian J Surg. 2009 Aug;71(4):177-81. doi: 10.1007/s12262-009-0059-7. Epub 2009 Sep 2.

Sivasubramaiyan K, Totey S, Bhat V, Totey SM, Deb K. (2009) Y-27632 enhances differentiation of blastocyst like cystic human embryoid bodies to endocrinologically active trophoblast cells on a biomimetic platform. J Biomed Sci, 16(1): 88.

Pal R, Totey S, Mamidi MK, Bhat VS, Totey S. (2009) Propensity of human embryonic stem cell lines during early stage of lineage specification controls their terminal differentiation into mature cell types. Exp Biol Med (Maywood), 234(10): 1230-43

Pal R, Venkataramana NK, Bansal A, Balaraju S, Jan M, Chandra R, Dixit A, Rauthan A, Murgod U, Totey S. (2009) Ex vivo-expanded autologous bone marrow-derived mesenchymal stromal cells in human spinal cord injury/paraplegia: a pilot clinical study. Cytotherapy, 11(7): 897-911.

Totey MS, Totey S, Pal R, Pal R. (2009) Adult Stem Cells: A Clinical Update. J Stem Cells. 2009;4(2):105-21.

Sivasubramaniyan K, Atluri RR, Sarda K, Arvind M, Balaji V, Deb KD. (2008) Endotoxin-induced silencing of mesoderm induction and functional differentiation: role of HMGB1 in pluripotency and infection. Regen Med, 3(1): 23-31.

Deb KD, Sarda K. (2008) Human embryonic stem cells: preclinical perspectives. J Transl Med, 29: 6-7.

Deb KD, Jayaprakash AD, Sharma V, Totey S. (2008) Embryonic stem cells: from markers to market. Rejuvenation Res, 11(1): 19-37

Saxena S, Hanwate M, Deb K, Sharma V, Totey S. (2008) FGF2 secreting human fibroblast feeder cells: a novel culture system for human embryonic stem cells. Mol Reprod Dev, 75(10): 1523-32.

Pal R, Hanwate M, Totey SM. (2008) Effect of holding time, temperature and different parenteral solutions on viability and functionality of adult bone marrow-derived mesenchymal stem cells before transplantation. J Tissue Eng Regen Med, 2(7):436-44.